Products

Vitamin K3-MSBC

    • Product Name: Vitamin K3-MSBC
    • CAS No.: 133-82-4
    • Chemical Formula: C12H9NaO5S
    • Form/Physical State: Powder
    • Factroy Site: No. 1 Xuelin Street, Haining, Zhejiang, China
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Jiangxi Brother Pharmaceutical Co., Ltd.
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    Specifications

    HS Code

    924459

    Chemical Name Menadione sodium bisulfite complex
    Other Names Vitamin K3-MSBC
    Appearance Yellow crystalline powder
    Solubility Freely soluble in water
    Molecular Formula C11H9NaO5S
    Molecular Weight 296.24 g/mol
    Stability Stable under dry conditions
    Storage Conditions Keep in a tightly closed container, protected from light and moisture
    Primary Use Vitamin K supplement in animal feed
    Odor Odorless
    Active Content 42%-45% min menadione
    Cas Number 130-37-0

    As an accredited Vitamin K3-MSBC factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Vitamin K3-MSBC typically features a sealed 25 kg fiber drum with a secure inner polyethylene liner for protection.
    Container Loading (20′ FCL) Container Loading (20′ FCL) for Vitamin K3-MSBC: Typically 10-12 MT per 20-foot container, packed in 25 kg fiber drums or bags.
    Shipping Vitamin K3-MSBC should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. Handle with care to avoid damage during transit. Transport according to local and international regulations for chemicals. Ensure proper labeling, and provide Material Safety Data Sheet (MSDS) with the shipment for safety and compliance.
    Storage Vitamin K3-MSBC should be stored in a tightly sealed container, kept in a cool, dry, and well-ventilated area away from moisture, heat, and direct sunlight. Store it at room temperature (generally 15–25°C). Avoid exposure to strong oxidizing agents and acids. Ensure containers are clearly labeled and kept away from incompatible materials to maintain stability and prevent contamination.
    Shelf Life Vitamin K3-MSBC typically has a shelf life of 24 months when stored in a cool, dry, and well-sealed container.
    Application of Vitamin K3-MSBC

    Applications of Vitamin K3-MSBC in Industrial Manufacturing

    Vitamin K3-MSBC (Menadione Sodium Bisulfite Complex) is widely valued for its stable, water-soluble source of vitamin K activity in several core industrial segments. As an authoritative manufacturer, we support direct use across animal nutrition premixing, commercial aquatic feed integration, companion animal dietary production, specialty vitamin premix blending, and certain pharmaceutical intermediate lines. Below we provide detailed, segment-specific application data.

    1. Compound Feed Formulation for Poultry

    Commercial poultry operations incorporate Vitamin K3-MSBC in vitamin and mineral premixes to prevent hemorrhagic syndromes due to vitamin K deficiency. Our material blends especially well in mash, pellet, or crumbled feed lines, serving as a consistent input for large-scale, automated production plants. Typical compounders adjust concentration based on breed, feed conversion rates, and regional raw material specifications.

    Industry compliance standards

    • GB 7300.1-2019 (China – Feed Additive Standards Regulations)
    • EU 1831/2003 (European Register of Feed Additives for Animal Nutrition)
    • AAFCO Official Publication (American Feed Control Officials’ Directory)
    • ISO 22000 Feed Safety Management Standards

    Typical usage ratio

    • 1–3 mg/kg of complete feed; adjusted according to line type, breed, and developmental stage

    Downstream process integration

    • Added in vitamin-mineral premix blending room; post-pelleting mixing for heat-sensitive formulations; solution for homogenous microdosing

    Final product types

    • Broiler starter/grower/finisher feeds
    • Layer and breeder mash feeds
    • Duck, goose, and turkey compound feeds
    • Enzyme-supplemented poultry nutritional packs

    2. Aquaculture Feed Manufacturing

    Aquafeed producers incorporate Vitamin K3-MSBC to ensure normal blood coagulation and bone metabolism in omnivorous and carnivorous fish species. The sodium bisulfite complex gives excellent water dispersibility, supporting wet and dry extrusion or compressed tablet production. Strict traceability and premix uniformity are enforced so downstream quality control meets certification audits.

    Industry compliance standards

    • FAMI-QS (Quality and Safety System for Specialty Feed Ingredients)
    • EU Regulation No 767/2009 (Marketing and Use of Feed)
    • ISO 17025 Laboratory Testing Accreditation
    • APEC Feed Safety Standards

    Typical usage ratio

    • 0.5–4 mg/kg of formulated aquafeed; varies depending on species (carp, tilapia, catfish)

    Downstream process integration

    • Formulated into micronutrient premixes before extrusion; applied as a dry blend for powdered starter feeds; integrated into oil-coated post-processing for floating and sinking pellets

    Final product types

    • Floating fish pellets
    • Shrimp and prawn grower feeds
    • Salmonid starter diets
    • Larval rearing micro-pellets

    3. Pet Nutrition and Supplement Manufacturing

    Pet food and supplement manufacturers use Vitamin K3-MSBC as a vitamin K activity enhancer in nutritionally complete dog and cat foods, supporting blood health and metabolic functions in processed kibbles, canned products, and functional treats. All integration steps are monitored for batch uniformity, trace contaminants, and declared label values under regulatory regimes spanning key markets.

    Industry compliance standards

    • AAFCO Dog and Cat Food Nutrient Profiles
    • FDA CFR Title 21 (Part 573, Food Additives Permitted in Feed)
    • FEDIAF Nutritional Guidelines (Europe)
    • Pet Food Manufacturing Good Manufacturing Practices (GMP)

    Typical usage ratio

    • Up to 2 mg/kg in finished feed, or as specified by AAFCO and FEDIAF for daily intake

    Downstream process integration

    • Blended into base vitamin premix; cold-mixed after hot extrusion; included in liquid flavor topdressing stage; incorporated via direct spray-drying for soft chews

    Final product types

    • Complete dry dog and cat food
    • Meat-based semi-moist pet foods
    • Functional nutritional supplements for pets
    • Pet treat and dental care sticks

    4. Industrial Vitamin Premix Production

    Premix blending facilities select Vitamin K3-MSBC as the preferred water-soluble active for multi-vitamin additive packs supplied to livestock (poultry, swine, cattle) premixers. Plants employ automated blending and strict sampling protocols to maintain batch-to-batch reproducibility and compliance with customer microdosing formulations for partner feed mills and integrator networks.

    Industry compliance standards

    • ISO 9001:2015 Quality Management
    • OECD GMP Feed Premix Production
    • FSMA (US Food Safety Modernization Act) for Animal Feed
    • HACCP Feed Premix Risk Management

    Typical usage ratio

    • 10–95 g per 100 kg vitamin premix, adjusted depending on final premix strength (concentrated vs. broad-spectrum)

    Downstream process integration

    • Weighing, microdosing, and powder blending under nitrogen atmosphere; periodic HPLC checks for active content; can be granulated for dust control if required by customer

    Final product types

    • Custom livestock vitamin premixes
    • Poultry and swine micro-premixes
    • Bagged micronutrient concentrates for trade and large farm end-use
    • Premix packs for extruded commercial feed plants

    5. Pharmaceutical Intermediates for Animal Use

    Veterinary pharmaceutical manufacturers use Vitamin K3-MSBC as a starting intermediate or active pharmaceutical ingredient (API) in water-dispersible dosage forms. Sourcing for this segment requires documented GMP traceability, validated impurity profiles, and certificate of analysis (COA) matching pharmacopoeia controls, especially for multispecies injectables or oral liquids.

    Industry compliance standards

    • Chinese Veterinary Pharmacopoeia (2020 Edition, Volume IV)
    • European Pharmacopoeia (Ph. Eur. 10.0: Veterinary Preparations)
    • GMP Regulation (EU) 2019/6 - Veterinary Medicinal Products
    • US Pharmacopeia (USP, Nonfood Animal Drug Standards)

    Typical usage ratio

    • API content as specified by final product (1-5 mg/mL in parent injectables; up to 50 mg/100 mL for oral suspension concentrates)

    Downstream process integration

    • Microdosing into solution tanks followed by sterile filtration; combined with adjuvants in injectable vials; suspension blending in oral preparation lines

    Final product types

    • Veterinary injectable ampoules for poultry and piglets
    • Oral liquid multivitamin supplements for ruminants and equines
    • Soluble powders for livestock water medication
    • Composite vitamin-mineral boluses

    Free Quote

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    Certification & Compliance
    More Introduction

    Vitamin K3-MSBC: Taking Animal Nutrition Further

    What Sets Vitamin K3-MSBC Apart

    Vitamin K3-MSBC stands on a foundation of manufacturing experience built over years of close work with animal feed producers, integrators, and veterinary nutritionists. We have learned from hands-on practice in large-scale production that the market asks for more than a simple vitamin additive. Clients want consistent, high-purity results and the kind of controlled, stable performance that supports both animal growth and farm profitability. Our focus on Vitamin K3-MSBC stems from seeing consistent customer demand for a product that responds well to automatic feed systems, blends smoothly in diverse formulations, and maintains active content across storage and pelleting.

    As a manufacturer, we are not removed from the day-in, day-out technical needs of commercial farms and feed mills. Instead, we adjust our production techniques to match real-world process conditions. Vitamin K3-MSBC does not look or handle like other forms of menadione. Its specific structure — menadione sodium bisulfite complex — gives greater stability against heat and moisture, a requirement brought up repeatedly by customers dealing with modern pelleting and extrusion equipment. Our engineers have refined production to reach a uniform, fine powder. This form allows direct dosing into premixes or full feeds without dusting or caking, a persistent complaint with earlier versions. Each batch undergoes routine checks in our own labs, where we focus on purity, sodium content, menadione value, and residual moisture, instead of relying on outside speculation or loose tolerance.

    Practical Usage in Animal Feeds

    Practicality governs the way Vitamin K3-MSBC gets applied in the field. It goes into poultry, swine, fish, and ruminant products because vitamin K is crucial for ensuring blood clotting and bone health, especially under the stress of rapid growth, processing, or disease. Many feed mills incorporate Vitamin K3-MSBC directly into vitamin-mineral premixes, which then flow through automated metering systems. The fine, dry texture prevents separation during long-distance trucking or storage in large silos. In water-soluble form, MSBC gets used for in-farm interventions where animals need a boost after vaccination, transport, or disease challenge.

    Working closely with animal health experts, we have observed no significant clumping or split layering in feed blends tested at varied humidity and pellet temperatures up to 90°C. On technical service visits, feedlot managers report that the MSBC form minimizes loss during mixing and ensures a more predictable dose per animal compared to older powders or liquids. This consistency matters for meeting nutritional intake targets and avoiding costly over-supplementation.

    Comparing Vitamin K3 Forms: Direct Experience

    Direct manufacturing experience gives us a clear view of how Vitamin K3-MSBC stacks against other forms like menadione sodium bisulfite, menadione nicotinamide bisulfite, or menadione dimethylpyrimidinol bisulfite. Customers switching from menadione sodium bisulfite often tell us about problems with dust, bulk density variability, or chemical instability, especially under fluctuating storage conditions. The MSBC structure improves shelf life because the menadione core bonds more securely, reducing the likelihood of oxidative breakdown.

    Feed manufacturers working with menadione nicotinamide bisulfite point out some similar heat-resistant properties, but many prefer MSBC because it achieves higher concentrations of active vitamin K3 per unit weight, letting them reduce overall additive costs. The sodium content also fits better with restricted salt programs in poultry diets, a minor adjustment that can make a significant difference in high-throughput integrated operations.

    Aquaculture nutritionists using alternative menadione forms raise concerns about water stability—MSBC stays in suspension longer, ensuring even intake in recirculating systems. Through batch trials using different extrusion methods common in the fish feed industry, we witness the product retaining a larger share of its active content compared to standard menadione products, which tend to degrade quickly under direct steam contact.

    Manufacturing Process and Quality Control

    Our own process starts with pharmaceutical-grade raw materials, sourced from primary suppliers with full analytical documentation. During synthesis, engineers adjust reaction timing and temperature profiles to maximize formation of the desired MSBC complex and minimize residual precursor compounds. After filtration, the product goes through a controlled drying sequence where temperature and airflow are carefully tracked. The goal is to drive off excess moisture while preserving the crystalline form which gives MSBC its stability and easy handling characteristics.

    In the packaging line, production records for every lot include photos of both bare and bagged product alongside spectral confirmation of active ingredient content. Only MSBC batches that meet our fixed specification ranges on particle size, bulk density, sodium ratio, and total menadione concentration advance to shipment. By focusing on real testing instead of statistical guesswork or unreliable proxies, we give peace of mind not only to purchasing managers but also to quality assurance teams who need clear documentation for farm audits and regulatory review.

    Storage and Handling Lessons from Experience

    Warehouse technicians working with Vitamin K3-MSBC do not struggle with the same pile-up, clumping, or absorption problems reported with older menadione powders. Outgassing issues are much less frequent, owing to the improved chemical stability of MSBC. In facilities with bulk storage or gravity feed systems, flow remains smooth as long as reasonable temperature control is maintained.

    We have encountered less need for special silos or humidity controls compared to past experiences with menadione sodium bisulfite. No severe odor complaints arise in adjacent storage rooms—a minor but practical benefit that matters in large agri-processing operations. Trucks arrive at client facilities with MSBC shipments showing a product as free-flowing and bright as when loaded, a direct outcome of both carefully managed production and selection of anti-caking agents proven safe for animal nutrition.

    Feedback from Feedmills and Integrators

    Most of the feedback we get comes directly from on-site visits or follow-up calls with plant managers and nutritionists. As feed mill capacity grows, so does the demand for additives that won’t back up the line, slow down mixing cycles, or require manual adjustments mid-batch. MSBC’s finer particle size eliminates need for extra screening before dosing, and there’s less residue left behind in dosing hoppers and labeling machines.

    Several international integrators tell us their QA procedures report fewer batch-to-batch variations after switching to MSBC, cutting down on costly finished product reprocessing. Laboratory results on vitamin retention show a tighter distribution compared to regular menadione sodium bisulfite, especially after pelleting. This isn’t theory—these are data points we receive from repeated, real-world batch results.

    Feed sales consultants add that end-users—especially poultry and ruminant operations—notice fewer unexplained drops in bone or leg health when using MSBC-enhanced diets. Consistent vitamin K levels in the feed translate to steady flock or herd performance, especially during periods of rapid growth or after stressful management changes in large production units.

    Understanding Market Demand and Product Safety

    We build every batch of Vitamin K3-MSBC for the practical, measurable demands of modern animal nutrition and health. The market expects more than routine compliance with regulatory vitamin K3 content levels. Instead, producers ask for clear evidence of batch stability through long storage and aggressive processing steps. To deliver on this, each shipment arrives with full analytical reports detailing active menadione content, sodium balance, moisture, and a heavy metals scan, supporting both buyer inspection and regulatory review.

    Product safety grows more important every year. Our teams monitor not only for unwanted contaminants, but also for pesticide residues, allergen risk, and prohibited microbial load. Our on-site QA staff regularly audit the process, sampling at each major stage, instead of pulling a token bag at the end. Long before any lot ships, we finish all in-house safety confirmations to avoid the headaches customers might face if an ingredient test fails downstream.

    Customer-driven product improvements define our approach. For example, past years saw a shift toward greater transparency in labeling and a preference for additive-free, low-dust forms. By paying attention to customer complaints and market trends, we have lowered the total additive load in MSBC without increasing costs. Feed manufacturers now can list fewer total excipients in their finished blends, easing approval for import and sale in tough-regulatory countries.

    Meeting the Needs of a Global Supply Chain

    Supplying global partners means we adapt shipping and documentation for each region’s specific animal feed laws and nutrition guidelines. Some markets demand tighter sodium limits, others prioritize exclusion of certain anticaking agents, while regions under organic or sustainable guidelines seek traceable raw materials and documented non-GMO sourcing.

    Our technical and regulatory groups meet regularly with international buyers to adjust product shipment documents, adapt packaging for local needs, and respond quickly if new labeling requirements appear. If batch problems arise during transit—a rare event, but always possible—our in-house support team leads root cause analysis by reviewing retained samples and production records right back to the source. This commitment keeps the supply chain moving, reducing lost time for feed mills and ensuring animals receive the nutritional profile intended by their producers.

    Sustainability and Environmental Impact

    Large-scale producers now think beyond short-term feed cost savings, and so do we. Our production of MSBC focuses on reducing waste streams and energy consumption at every process step. By raising yield from each batch of menadione synthesis, we cut down on the amount of byproduct material. Steam and wastewater recycling in our facility saves water and keeps our environmental footprint smaller than conventional manufacturers who ignore downstream waste handling.

    We also invest in safer worker conditions: improved air handling, dust containment, and ergonomic packaging lines mean fewer health and safety complaints—something we measure firsthand by annual worker health surveys and low turnover. Our clients, especially those selling into export markets, increasingly request sustainability certifications or carbon footprint analyses. Over the past two years our technical team has developed batch-level environmental impact sheets, confirming key indicators like total water use and CO2 emissions per kilogram of MSBC produced.

    Looking Ahead: Product Innovation and Research

    We collaborate directly with research institutions studying animal micronutrition. Current projects focus on improving absorption of vitamin K3 forms in monogastric and ruminant animals and minimizing cross-reactions with other mineral feed ingredients. In-house, our R&D teams experiment with slow-release coating technologies, aiming to further boost retention of MSBC in high-stress pelleting or extrusion. Upcoming pilot studies with university partners track animal growth, vitamin status, and health outcomes in larger cohorts, not just lab models.

    The feedback loop between lab bench, production line, and customer experience shapes all future improvements. As new animal nutrition data emerges—whether on the effects of vitamin K3 deficiency or the role of micronutrients in immune health—we adapt both our technical processes and quality assurance routines. Unlike commodity traders, we keep hands-on responsibility throughout the MSBC journey, from molecule to final product delivery. This direct accountability gives our customers confidence and sets a high bar for transparent, ethical manufacturing in the vitamin additive industry.

    In-Field Performance: Practical Examples

    Our on-site monitoring in customer farms, aquaculture sites, and feed mills goes beyond basic technical support. By observing Vitamin K3-MSBC in routine flock management or in response to local disease challenges, we see how real-world conditions shape both performance and perception of our product. For instance, in tropical markets where high heat and humidity can ruin less stable products, MSBC continues to deliver active content well past expiration dates set by international standards. In controlled tests alongside standard menadione sodium bisulfite under identical warehouse conditions, MSBC shows a slower rate of degradation, a statistic confirmed by regular third-party testing.

    Producers serving local and international chain retailers demand traceability and ‘farm-to-feed’ transparency. We keep detailed batch records stretching back to raw material intake, enabling prompt response if regulatory bodies or end-users raise questions about nutrition or safety. We have seen that this practice not only ensures regulatory compliance, but also builds lasting trust with repeat clients, especially in regions where recall risk or import rejections can sink business relationships overnight.

    Technical Support and Troubleshooting

    Our product managers and technical service staff regularly conduct on-site checks for mills or farms facing unexpected results. By seeing equipment in action—whether ancient rotary mixers or the latest twin-shaft rapid blenders—we tune MSBC handling advice for each plant setup. Common issues, such as dust escape in high-speed lines or residual moisture buildup in premix tanks, get resolved using field-tested solutions learned from similar facilities worldwide.

    Some clients encounter unexpected caking in certain climates; based on our long field track records, we recommend immediate adjustments in storage temperature or mixing order instead of temporary workarounds. Shared experience from decades in the business means we solve most problems before they develop into production bottlenecks. We also update our handling guides every quarter based on new feedback and data—a process driven by real batches, not just printed manuals.

    Regulatory Trends and Compliance Preparedness

    The landscape for feed additives tightens every year. We keep a legal and regulatory team on hand to study updates in global rules, so clients receive not only a product that meets published specifications, but also one pre-validated for changing international requirements—whether on impurities, residual solvents, or new limits on mineral additives. Where import authorities demand retrospective traceability, our document system means every MSBC shipment leaves a clear audit trail.

    Feed manufacturers often ask us for data supporting claims on stability, safety, and active ingredient retention in finished feed. We supply standardized certificate packs for every shipment and conduct additional in-house testing when new rules appear unexpectedly in key export markets. Direct control over manufacturing—not relying on traders or outside blenders—lets us update production specs rapidly if standards change.

    Partnering with Customers for Long-Term Performance

    Lasting customer partnerships come from being willing to visit, advise, and respond quickly, not just fill orders. We view Vitamin K3-MSBC less as a simple feed input, more as an integrated tool for animal health management. Feedback from our most demanding clients—many of whom operate hundreds of thousands of animal places—tells us that our approach to quality, traceability, and product improvement supports both compliance and animal welfare, key goals for the future of responsible agriculture.

    Looking forward, we remain committed to close communication with nutritionists, QA staff, and procurement officers at every stage of the supply chain. Our hands-on experience, technical depth, and willingness to adapt let us build better products and stronger partnerships day after day in a complex and changing feed industry.