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HS Code |
666285 |
| Product Name | Thiamine Hydrochloride |
| Chemical Formula | C12H17ClN4OS |
| Molecular Weight | 337.85 g/mol |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water |
| Melting Point | 248-250°C (decomposition) |
| Cas Number | 67-03-8 |
| Ph Value | 2.1–2.6 (10% solution) |
| Odor | Odorless |
| Storage Conditions | Store in a cool, dry place, protected from light |
| Synonyms | Vitamin B1 hydrochloride |
| Purity | Typically ≥98% |
| Stability | Stable under recommended storage conditions |
| Uses | Nutritional supplement, pharmaceutical ingredient |
| Bioavailability | High when administered orally |
As an accredited Thiamine Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Thiamine Hydrochloride, 500g; packaged in a sealed, amber plastic bottle with a tamper-evident cap and clear labeling. |
| Container Loading (20′ FCL) | 20′ FCL (Full Container Load) for Thiamine Hydrochloride: 8-9 metric tons per container, packed in fiber drums or cartons with pallets. |
| Shipping | Thiamine Hydrochloride is shipped in tightly sealed containers, protected from light and moisture. It is typically transported as a non-hazardous material under normal conditions, following standard chemical handling protocols. Packaging ensures the product remains stable, dry, and contamination-free during transit, complying with relevant safety and regulatory shipping requirements. |
| Storage | Thiamine Hydrochloride should be stored in a tightly closed container, protected from light and moisture. It should be kept at room temperature, ideally between 15°C and 30°C (59°F to 86°F). Ensure the storage area is dry, well-ventilated, and away from incompatible substances. Avoid exposure to excessive heat or direct sunlight to maintain its stability and effectiveness. |
| Shelf Life | Thiamine Hydrochloride typically has a shelf life of 24-36 months when stored in a cool, dry place in tightly sealed containers. |
Applications of Thiamine Hydrochloride in Industrial ManufacturingAs the direct manufacturer of thiamine hydrochloride, we supply high-purity material for specialized industrial markets that require precise formulation control and strict regulatory compliance. The following application scenarios reflect established downstream sectors where thiamine hydrochloride is a critical input, each with unique quality requirements and process integration demands. 1. Fortified Food and Beverage ManufacturingFood processors use thiamine hydrochloride as an essential nutrient additive in the enrichment of cereals, flour, and beverage formulations to address regulatory-driven vitamin B1 fortification requirements. Formulation engineers balance dosage to maintain stability during high-shear, thermal, or wet processing stages, while adhering to local food additive statutes. Automated inline addition systems integrate thiamine hydrochloride at specified flow control points, minimizing loss and ensuring label compliance for enriched finished goods. Industry compliance standards
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2. Veterinary Premix and Animal Nutrition FeedAnimal feed manufacturers incorporate thiamine hydrochloride as a stable B1 vitamin source into premixes for poultry, livestock, and aquaculture sectors. Nutritional experts select particle sizes for uniformity and bioavailability, ensuring compliance with stringent feed safety regulations. During large-scale mixing operations, automated feeders dispense thiamine to avoid dusting and cross-contamination, supporting the production of vitamin-standardized compound feeds and supplements. Industry compliance standards
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3. Pharmaceutical Tablet and Injectable FormulationPharmaceutical companies formulate thiamine hydrochloride as a precise API in oral tablets, effervescent powders, and injectable forms for human therapeutics. Manufacturing follows pharmacopoeial monographs, incorporating strict environmental and microbial controls. During tableting or ampoule filling, real-time quality checks verify API concentrations, and customized granulation or liquid mixing technologies are deployed to maintain active ingredient homogeneity and bioactivity for the final dosage forms. Industry compliance standards
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4. Nutraceuticals and Dietary Supplement BlendingProducers of functional foods and dietary supplements utilize thiamine hydrochloride for multivitamin tablets, gummies, capsules, and fortified drink powders targeting consumer markets. Product developers map thiamine content to regional upper daily intake limits and combine it with other water-soluble vitamins, controlling release profiles through coating or matrix selection. Integrated process controls synchronize vitamin feeding with high-speed tableting, encapsulation, or liquid blending to achieve consistent active levels per serving. Industry compliance standards
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5. Infant Formula and Clinical Nutrition ProductionInfant formula and clinical enteral nutrition manufacturers incorporate thiamine hydrochloride to meet strict compositional standards for early-life and therapeutic nutrition. Technical teams balance stability during UHT sterilization and spray drying to minimize losses and guarantee labeled B1 levels in the reconstituted product. In-process controls monitor vitamin recovery through each production step, ensuring compliance with tight quality and safety benchmarks for end-user safety. Industry compliance standards
Typical usage ratio
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Competitive Thiamine Hydrochloride prices that fit your budget—flexible terms and customized quotes for every order.
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Email: sales7@bouling-chem.com
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Thiamine Hydrochloride plays a pivotal role across food, feed, and pharma industries. Decades in chemical manufacturing reveal that customers expect consistency, verified purity, and reliable supply above all else. Rather than view Thiamine Hydrochloride simply by its monograph or as a commodity, our team approaches it as a foundational ingredient that touches animal health, human nutrition, and a wide span of specialty formulations. Our model—produced from pharmaceutical-grade sources and with a rigorous in-house analytics program—reflects a focus on real-world end use, not just ticking regulatory boxes.
Thiamine Hydrochloride arises as the hydrochloride salt of vitamin B1. Its chemical stability, water solubility, and compatibility with various carriers and excipients support its use in everything from oral tablets to fortified premixes. Our facility utilizes validated crystallization and drying methods to maintain a stable, bright white or off-white fine powder. This exact appearance matters: reliable manufacturers know that darkening, caking, or clumping affect downstream mixing and customer confidence. Every lot receives verification by HPLC and titration methods—methods that go well beyond simple bulk testing, because inconsistency at this level quickly becomes visible in end-user complaints and returns.
B1 deficiency leads to both clinical illness in humans and production problems in livestock. In our experience, downstream users—food companies, nutritionists, and feed formulators—rarely want to chase batch variability or functional problems. People relying on our bulk ingredient trust that solubility, particle size, and active content match not just USP or EP specifications, but also the way the vitamin actually behaves in their blend. We have seen how even a 1% deviation in thiamine HCl assay can alter fortification levels across a run of infant formula or feed ration. Lessons from the early years taught us to never compromise on on-site analysis. That attention to assay and contamination has helped us grow long-term supply relationships with strict buyers who audit production regularly and expect full traceability.
In pharmaceuticals and dietary supplements, Thiamine Hydrochloride appears mainly in multivitamin tablets and injections. Manufacturers often focus on ease of blending, compressibility, and reactivity with other actives in the mix. From the production floor, we know that bulk density and flow properties demand regular monitoring, especially for large-scale tableting operations. Fine-tuning particle size reduces sticking and ensures accurate dosing per tablet, meeting both quality and regulatory requirements.
The history of thiamine’s use in medicine stretches back over a century. We continue to provide pharmaceutical-grade material that aligns with monographs from the US, Europe, and elsewhere, while taking extra measures on impurity profiling and residual solvent analysis. There’s a reason experienced brands often conduct side-by-side bench tests before choosing a supplier—variability in odor, taste, or dissolution can disrupt years of formulation work. Each year, our lab works alongside quality control partners to troubleshoot and optimize batches for clients with new delivery formats or changing formulation guidelines.
In direct supplementation—such as B complex capsules, effervescent powders, and direct compressible tablets—our thiamine HCl handles well through multiple processing steps. Over time, we have refined our drying and sieving to minimize dusting and improve mixing in automated lines. The small details make a difference; customers tell us that reliable handling saves both time and labor.
Animal nutrition presents unique challenges. In the feed sector, premix producers and integrators look to us for a reliable thiamine HCl that withstands pelleting, extrusion, and long-haul transport. We leverage our experience with micronutrient blending and physical property control to keep the powder free-flowing even in high-humidity conditions or prolonged storage. This matters to feed mills that operate continuously, because a sticky or agglomerated ingredient can bring production to a standstill and cause expensive batch losses.
Livestock—such as poultry, swine, and dairy cattle—depend on steady intake of B vitamins for basic metabolism and immune health. Many suppliers offer thiamine sources, but our team pays attention to both bioavailability and contaminant monitoring. Decades of feedback reveal that users notice the difference when mixing is uneven or nutrient value drifts across bags. We have invested in trace element screening and toxin residue controls that exceed standard regulatory demands. Practical experience shows that animal performance, measured in feed conversion and weight gain, tracks closely with micronutrient integrity from batch to batch. That knowledge shapes every run in our plant, and our customers’ repeat orders show that attention to detail translates to real value in the field.
Food manufacturers count on consistent B1 input for fortification programs in flour, cereals, infant formula, and sports nutrition mixes. Precision matters at this scale, as even a slight variation can over-deliver or under-deliver on label claims. Since fortification often crosses borders and standards shift between regions, we built our validation program to support a range of local and international standards—without cutting corners.
Our food-grade Thiamine Hydrochloride undergoes a thorough review in every production batch for microbial contamination, heavy metals, and allergen status. Over years of customer audits, our documentation trails and transparency help buyers verify every critical quality attribute. We update our protocols regularly to stay ahead of evolving food safety expectations, and maintain open channels with stakeholders for feedback and troubleshooting. For example, customers producing gluten-free and hypoallergenic foods can rely on us for dedicated production lines, strict cross-contamination prevention, and validated cleaning procedures.
One issue rising to the forefront is label transparency and non-GMO documentation. Many food fortification buyers now demand proof of raw material origin and absence of genetically engineered inputs. Early on, we responded with expanded certification and chain-of-custody controls, recognizing that reputation with food producers rests not just on technical purity but on full public confidence in every lot.
Some users ask about the differences between Thiamine Hydrochloride and other thiamine salts, such as Thiamine Mononitrate. The choice depends on several practical factors. While both sources address the vitamin B1 requirement, their solubility and chemical stability show key contrasts. Our experience shows Thiamine Hydrochloride offers higher water solubility, making it useful in liquid applications, wet granulated blends, and injectables. Mononitrate forms tend to excel in dry blends and some tableting applications thanks to their lower hygroscopicity. We share these details with formulators because using the wrong form can trigger unexpected changes in product shelf stability or performance, especially in climates with high ambient humidity.
Some products call for slow-release or heat-stable performance, leading manufacturers to seek out alternative derivatives. Yet most routine fortification—particularly where water solubility or direct compressibility matters—still favors the hydrochloride form. Collaborations with technical teams across food, feed, and pharma sectors help us guide the most appropriate material selection every time.
Reliability does not start or end with test results in the lab. Over many years in chemical production, we witnessed plenty of instances where unexpected disruptions—supply chain interruptions, shifts in raw material pricing, or regulatory inspections—upend industry norms. We managed challenges ranging from pandemic-era transport delays to sudden changes in international ingredient registration. Our approach always centers on open communication with partners, investments in buffer stocks, and constant process review to close any gaps. That has proven key for feed and supplement manufacturers facing just-in-time inventory or tight regulatory reviews.
Manufacturers who operate globally must manage changing residue requirements, allergen notifications, and the scrutiny of both large customers and inspectors. Beyond batch approval, we document every lot’s chain of custody from starting material to finished drum. Our plants maintain full compliance with ISO quality management, and we submit to independent audits—even unannounced. Customers tell us these safeguards provide peace of mind as they themselves face tougher scrutiny from retail brands and regulators.
Environmental management grows more central each year. Responsible production of Thiamine Hydrochloride spans careful effluent monitoring, energy efficiency upgrades, and reduced solvent use. We continuously invest in closed-loop water management and innovative waste minimization approaches. Our current catalyst recovery project targets reductions in process emissions and offers further cost savings that can be passed along to our partners.
Customer concerns increasingly touch on the environmental footprint of micronutrient production. We initiated partnerships with local waste handlers and environmental groups to further reduce impact, sharing data transparently with interested buyers. Committing to lower environmental burdens requires day-to-day vigilance, and the lessons we learn roll straight into future process design. By providing documentation and traceability on every lot, we support food producers looking to highlight sustainable sourcing and low-impact inputs on their labels.
Experience shows that no production run is ever truly routine. Each new batch or formulation request can introduce subtle changes in equipment, ingredient handling, or end-customer requirements. Our technical support begins with direct dialogue: troubleshooting at the formulation stage, providing both standard analytics and application notes, and offering on-the-ground troubleshooting where issues arise. Many of our product improvements originated as customer suggestions—simplified packaging, custom mesh sizes, or documentation tailored for regulatory submissions. By maintaining a real-world view and staying close to our end users, we adapt quickly and refine our processes from the inside out.
We understand that global supply chains face growing demands for accountability, immediate documentation, and rapid response to audits. Years of experience in the trenches have ingrained a deep respect for these expectations. Our document management systems offer instant access to certificates, analytics, and ingredient origins for each lot. That approach has helped our buyers satisfy not only governmental agencies but also internal review teams and downstream customers with zero tolerance for uncertainty. As new technologies expand traceability capabilities, we adopt them with enthusiasm, reinforcing trust in every partnership we hold.
Market expectations never stand still. As customers face novel challenges—whether new health regulations, evolving delivery methods, or regional labeling requirements—innovation becomes non-negotiable. We direct a portion of annual revenue into targeted R&D, focused both on incremental process improvements and longer-term formulation options. Some of the most exciting work underway in our labs involves novel blending methods with engineered excipients, reductions in residual solvent levels, and advanced impurity screening. Partners lean on us for technical insights, and we keep them updated as fresh options emerge from development.
Before scaling any process change, our project managers consult directly with downstream manufacturers and, where relevant, regulatory advisors. That style of partnership goes beyond the transactional, aiming for solutions that avoid disruptions and strengthen everyone’s market position. Market-driven R&D will remain a central part of our business well into the future.
Working at the core of chemical manufacturing for multiple decades provides a unique vantage point on the evolution and relevance of ingredients like Thiamine Hydrochloride. Quality and reliability do not arise by accident. They stem from hard-fought experience, careful investment, and a willingness to listen to feedback long after product leaves the loading bay. If recent disruptions have taught us anything, it’s that people value not just technical conformity but confidence—the kind earned with every shipment, every traceable lot, and every technical engagement.
Ingredient manufacturers shape industry standards with every lot produced. Our approach keeps transparency and partnership at the center, prioritizing vigorous quality control, proactive environmental management, and a deep commitment to the real-world success of our customers. Thiamine Hydrochloride remains much more than a simple raw material; it serves as a window into the discipline, reliability, and innovation that define the manufacturing side of the modern ingredient supply chain.
The ongoing journey to produce, refine, and deliver Thiamine Hydrochloride matches our broader mission: to raise the standards of chemical production while supporting downstream partners through every challenge and opportunity ahead.