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HS Code |
488165 |
| Product Name | Vitamin B3 Nicotinic Acid |
| Chemical Name | Nicotinic Acid |
| Alternative Names | Niacin |
| Molecular Formula | C6H5NO2 |
| Molecular Weight | 123.11 g/mol |
| Physical Appearance | White crystalline powder |
| Solubility | Soluble in water |
| Main Function | Supports energy metabolism |
| Recommended Daily Intake | 14-16 mg for adults |
| Primary Sources | Meat, fish, nuts, grains |
| Deficiency Symptoms | Pellagra, dermatitis, diarrhea, dementia |
| Stability | Stable under normal storage conditions |
| Storage Conditions | Store in a cool, dry place |
| Cas Number | 59-67-6 |
| Uses | Dietary supplement, treatment of niacin deficiency |
As an accredited Vitamin B3 Nicotinic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White HDPE bottle with blue label, marked "Vitamin B3 Nicotinic Acid, 100g." Features safety seal, batch number, and hazard symbols. |
| Container Loading (20′ FCL) | Container Loading (20′ FCL) for Vitamin B3 Nicotinic Acid: typically 12-13 metric tons, packed in 25kg drums or bags, ensuring secure, moisture-proof shipment. |
| Shipping | Vitamin B3 Nicotinic Acid is shipped in tightly sealed, food-grade containers to prevent contamination and moisture exposure. Packaging complies with safety and regulatory guidelines. The containers are clearly labeled and handled with care, typically shipped at ambient temperature, and accompanied by appropriate documentation to ensure safe and compliant delivery. |
| Storage | Vitamin B3 (Nicotinic Acid) should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, ideally at room temperature between 15°C and 30°C (59°F and 86°F). Ensure it is kept away from incompatible substances, such as strong oxidizing agents, and out of reach of children and unauthorized personnel. |
| Shelf Life | Vitamin B3 Nicotinic Acid typically has a shelf life of 36 months when stored in a cool, dry place, away from light. |
Applications of Vitamin B3 Nicotinic Acid in Industrial ManufacturingAs the direct manufacturer of Vitamin B3 Nicotinic Acid, we supply high-purity material tailored for integration into key industrial sectors. Our production supports strict regulatory requirements and provides formulation expertise for diverse application contexts. Below we detail the principal industrial sectors, specific to the actual use of Nicotinic Acid, where our product delivers measurable value in downstream production chains. 1. Food and Beverage FortificationFood and beverage processors incorporate Nicotinic Acid to enrich cereals, flour, dairy, beverages, and meal replacement products, meeting nutritional labeling and fortification demands. Our material integrates into the blending or mixing stage, ensuring consistent nutritional enhancement in processed foods. End-user manufacturers carefully measure addition levels in line with approved maximums for safe human consumption. Our expertise helps clients navigate formulation challenges like uniform dispersal and stability during thermal processing. Industry compliance standards
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2. Feed Additives (Animal Nutrition)Nicotinic Acid is indispensable for animal feed premix formulators aiming to achieve balanced vitamin nutrition in aquaculture, poultry, swine, and ruminant diets. Our material demonstrates reliable flow and uniformity during premix blending and pelleting. Animal nutrition specialists precisely adjust inclusion rates to livestock type, life stage, and feeding regime, within authorized limits to meet growth performance and animal welfare objectives. Comprehensive traceability and batch consistency support feed safety audits across international markets. Industry compliance standards
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3. Pharmaceutical Formulation (APIs and Intermediates)Our Nicotinic Acid meets international pharmacopoeial standards for use in solid and liquid pharmaceutical formulations. Drug manufacturers use it as an active pharmaceutical ingredient (API) in niacin tablets and sustained release preparations or as a chemical precursor for derivatives. We offer GMP-compliant traceability and secure batch records, supporting DMF submissions and regulatory inspections for oral dosage manufacturing. We provide technical documentation to facilitate product registration across regulated markets. Industry compliance standards
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4. Cosmetic and Personal Care IngredientIn the cosmetics sector, manufacturers integrate Nicotinic Acid for its established role in skin conditioning and hair care. It functions as a recognized ingredient in face creams, serums, scalp treatments, and hair growth formulations, often in combination with other vitamins and botanical actives. Cosmetics chemists optimize dosage to ensure performance with minimal irritation risk, confirming compliance with ingredient lists and claim substantiation standards. Robust documentation supports product safety and market entry across jurisdictions. Industry compliance standards
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5. Electroplating and Surface Treatment ChemicalNicotinic Acid serves a specialized use as a brightener and leveling agent in the electroplating industry, primarily within nickel and zinc plating applications. Its addition refines metal deposit integrity, reduces pitting, and enhances surface gloss. Plating bath operators calculate usage according to bath chemistry, current density, and metal type, maintaining effective concentrations for batch longevity. Documentation tracks purity and stimulus-response for industrial process improvement, meeting stringent HSSE and finished component quality documentation standards. Industry compliance standards
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6. Industrial Catalyst and Intermediate Chemical SynthesisChemical manufacturers utilize Nicotinic Acid in synthetic pathways such as the production of pyridine derivatives, intermediates for veterinary medications, and active catalysts for industrial reactions. Its purity ensures reproducible batch yields and minimizes side reaction risks. Process chemists select addition points based on pathway stage and intended molecular transformation. Stringent process monitoring and batch analysis deliver reliability across repeated campaigns, facilitating quality documentation for downstream industrial customers. Industry compliance standards
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Producing nicotinic acid, also known as vitamin B3, requires more than just technical expertise. Our facility maintains a close relationship with every step of the process, from raw material selection to the finished product, so we know the reality of what goes into each batch. As a water-soluble vitamin, nicotinic acid carries vital importance for the human body. It supports cellular metabolism and contributes to energy production. Over the years, we have seen increased demand for this compound from the food, nutrition, pharmaceutical, and animal feed industries. Each market places specific requests on product quality and performance, pushing us to refine our processes.
The grade our clients ask most for remains pharmaceutical and food-grade nicotinic acid. We manufacture a crystalline powder, often requested at the 99.5% purity level and higher. The color holds as a white to almost white crystal, reflecting both purity and the absence of contamination. Granulometry tends to follow customer demand—most buyers need a particle size below 500 microns to ensure smooth blending and dissolution. In our own process, careful drying and controlled crystallization produce a consistently free-flowing powder, so downstream handling does not cause headaches.
Moisture content often causes arguments, but we keep it under 0.5% by weight. This figure, though small, makes a difference in shelf life and mixing behavior. We process in batches, with every lot passing through multiple rounds of sampling and HPLC or titration-based assays. Heavy metal and arsenic contents are usually well below global regulatory limits because raw material traceability forms a core value for us. We employ a multi-step purification approach, making sure no batch leaves our line with unknown impurities present above specification.
In our years of supplying nicotinic acid, we have seen how formulations evolve. Human nutritional supplements remain the most visible market, whether as tablets, soft gels, or sachet powders. Vitamin B3 supplements draw on published evidence connecting nicotinic acid to cholesterol management, circulation improvement, and skin health. Nutritionists working with us specify tight controls over impurity levels, and opt for non-GMO materials, so we have adapted our protocols. Our production keeps allergens and cross-contaminants out, and every batch meets the requirements for major global markets.
In animal feeds, nicotinic acid becomes a standard dietary additive, supporting metabolism and feed conversion. Premix producers require a product that handles well, resists caking, and combines efficiently with other micronutrients. Pelleting temperatures can challenge vitamin stability, so we always monitor both raw material origin and processing temperatures, knowing vitamin potency loss means money down the drain for animal nutritionists. We gather feedback directly from feed formulators so our technical support can address storage or mixing questions.
Pharmaceutical-grade nicotinic acid faces even stricter tests for purity and uniformity. Drug producers monitor not just purity and heavy metals but also testing for specific related substances and residual solvents. We have invested in improved chromatography and batch traceability based on years of audits and customer demand. Producers of solid oral dosage forms value these upgrades because any deviation from the monograph puts years of market access at risk.
Food industry partners look at aspects like solubility in water, ease of dispersal in beverages, and compatibility with other nutrients. Some applications, like ready-to-drink beverages, need ultra-rapid dissolution. In response, we shifted part of our production to extra fine grades, using air-milling and enhanced surface finishing. We continue to study and discuss the differences these process changes make, since customer success in product launches reflects directly on us.
Often, clients compare nicotinic acid to other B vitamins like niacinamide, folic acid, or riboflavin. These comparisons bring out not just chemical differences, but real-life implications for use and performance. For example, niacinamide (nicotinamide) and nicotinic acid both count as vitamin B3. Niacinamide does not cause the skin “flush” sometimes linked with nicotinic acid, which matters in fortified food and supplement applications. But only nicotinic acid delivers documented effects on cholesterol and blood lipids, which nutritional scientists continue to study. We maintain separate production lines for both forms, with cleaning and cross-checks so no batch mixes by mistake.
Other B vitamins differ greatly in stability, solubility, and organoleptic impact. Riboflavin, for example, imparts a yellow color and can have an off odor—nicotinic acid remains nearly odorless and colorless, making it preferred for certain applications. Folic acid degrades faster under heat and light, so packaging and process design focus on protecting the finished product. In contrast, typical stabilized nicotinic acid survives most processing and storage conditions intact, though we still advise customers of limits for exposure to high temperatures or direct sunlight.
Study of inter-compatibility between nutritional premixes is ongoing. Each has its place in human and animal nutrition. Our own involvement means regular lab studies to assess interactions, particularly in multivitamin blends. Real-life production often throws unexpected mixing or stability challenges, which industry best practices alone cannot solve. Our input—backed by ongoing batch testing—has prevented more than one costly recall or shelf life complaint for our partners. Vitamin B3’s balance between stability and metabolic effect gives it an edge in many nutraceutical and therapeutic applications.
Over two decades, we’ve answered countless questions from customers and regulators. Each interaction teaches lessons that echo through our production philosophy. At scale, slight oversights—such as impurity drift, micron size variation, or pH fluctuation—can lead to disruptions in formulation or unwanted effects in the end-use. Tight production controls and repeated verification keep problems off our customers’ tables. Recall events cost far more than conscientious batch control. Our experience tells us that full traceability, transparency in documentation, and fast technical support make the difference between a smooth product launch and a regulatory headache.
Several years ago, a major food fortification project encountered unexpected color instability in bulk vitamin blends. Root cause analysis showed a poorly controlled particle size distribution, causing uneven mixing and subtle color shifts. Our intervention involved close work with the blend manufacturer, introducing tighter sieving and adding a secondary homogenization step at our factory. The next batches showed even dispersal and stable color, which restored customer confidence and averted potential end-user complaints.
In another case, an animal feed customer faced caking issues during shipment to a humid region. Routine drying and packaging, proven in our climate, failed under tropical humidity at destination. Instead of a simple assurance, we re-examined packaging options, trialed thicker liners, and ran shipping simulation tests at higher humidity and temperature. Results led to a new standard with higher barrier packaging and improved desiccant use. Long-term partnerships rely on these practical, responsive solutions based on real-world conditions, not just desk-side assurances.
As food, supplement, and pharma regulation grows more complex each year, we never take compliance for granted. Product recalls, import rejections, or off-spec delivery each deliver lessons about proper documentation and claim support. For us, regulatory inspections and customer audits act as opportunities to strengthen our systems. Our internal monitoring extends to both raw material input and waste output, so we act early if we detect a trend toward higher impurity levels. Our laboratory staff don’t just run QC samples—they monitor patterns, spot deviations, and recommend process tweaks before the product leaves the factory.
Global harmonization has improved confidence, but no two regulatory bodies are identical. European food and pharma laws evolve differently from US, Chinese, or Latin American standards, and individual clients often follow stricter-than-required specifications. We maintain dialogue with customer technical teams so label claims, certificates of analysis, and batch release protocols align with each market’s expectations. Regular staff training and cross-lab proficiency checks keep our certification status strong. We stay current on changes to monographs and legal requirements, from USP and EP down to domestic pharmacopeias.
Downstream customers may not see every behind-the-scenes step, but we share full documentation, impurity profiles, and stability data. For long storage and transit, we factor in shelf life projections, recommend stock turnover times, and occasionally consult on customer storage setups. If an issue does arise, we have seen that quick, transparent response prevents escalation. Packing the right information into our outgoing paperwork has avoided more than one customs delay or regulatory stoppage.
No factory system stands still. In our line, upgrading plant equipment brings the challenge of balancing speed, footprint, and operational safety. Last year’s move to semi-automated sieving and bulk packaging systems reduced physical handling and improved consistency across large-volume orders. We improved our dust collection protocol at the same time, with the welcome side effect of cleaner air inside the plant and less cross-exposure risk between neighboring lines. Small day-to-day tweaks—improved cleaning procedures, tighter humidity control, real-time data loggers—each contribute to a more reliable product and safer work environment.
We hold regular “lessons learned” briefings, where plant staff, QA, and logistics teams share recent wins and pain points. Openness in reporting helps catch procedural blind spots. Our technical team works with industry consultants, suppliers, and downstream users to verify that process changes translate to meaningful benefits. Small improvements—shorter ingredient delivery times, new sieve mesh recommendations, improved drum closures—often stem from these feedback cycles.
Research and development does not only mean pursuing new molecules. Most of our innovation work revolves around improving purity, reducing process waste, extending shelf life, and making logistics more trouble-free for buyers. Studying analytical trends and customer feedback points us where to act next. Every time we see a batch deviate—even within specification but showing an unusual trend—we trace the root, apply corrective action, and adjust procedures to avoid future surprises.
Every application imposes unique technical and commercial demands. Supplement makers want ultra-high purity and zero allergen risk; animal nutrition users need robust powder handling and cost efficiency; pharmaceutical partners seek absolute traceability and regulatory assurance. We have learned to collaborate both with large multinationals and regional specialists, always sharing technical insights that help head off issues before they turn into lost production or regulatory lapses.
Occasionally, misunderstanding about “flush” effects or inter-conversion among B3 forms leads to unnecessary reformulation. We share not just product but background science, clarifying which use scenarios fit best with nicotinic acid and where a switch to niacinamide makes sense. We back claims with supporting literature and explain any differences in expected metabolic response. This builds trust and positions us as more than a commodity supplier.
Bulk handling creates another set of challenges. Each downstream facility differs in bin design, mixing technology, and local climate. Input from end-users helps refine our advice on best storage, shelf life extension, and re-testing protocols. Where critical, we run trial shipments or pilot-scale blending to ensure actual customer setups match theoretical compatibility.
International logistics brings separate headaches: shifting customs requirements, volatile transit conditions, and widely varying expectations around stability and labeling. Our export staff track and adapt to the demands of different routes and regulatory checks, often pre-preparing documentation or adjusting packaging type to accelerate customs clearance in challenging regions.
Demand for vitamin B3 continues to grow, driven by emerging health trends and increased awareness of micronutrient deficiencies. Potential new markets, such as functional foods, energy drinks, and processed animal feeds, always force us to review current product lines and packaging options. Direct connection with formulators gives us early warning about shifting requirements for allergen avoidance, non-GMO status, or compatible excipient lists.
One recent trend goes toward “clean label” products, where simplicity and transparency in ingredient sourcing and processing matter. Traceability has become central: more customers ask for full supply chain documentation, right down to certificate of origin for key inputs. We’ve worked with our own suppliers to build auditable sourcing and strengthen both upstream and downstream transparency. These efforts add real value instead of inflating marketing claims.
Automation and digitalization promise added efficiency and real-time batch monitoring. By linking plant data directly to the quality lab, we spot drift and outliers without waiting for end-of-lot checks. This helps in continuous process control and gives our team added tools to catch any trends before they matter at the customer end.
Continued drive to cut environmental impact shapes how we procure, process, and package. Wastewater handling, energy use, and packaging reduction face ongoing review, and we report annual data trends both internally and to key downstream partners. Customer audits now often include sustainability, so we invest in process improvements that reduce footprint and meet new expectations. These practical steps—leaner water use, efficient reactors, smarter packaging—deliver both compliance and cost savings.
In our daily work, producing nicotinic acid never feels like routine. Every batch represents a visible outcome of careful process design, ongoing improvement, and real market feedback. Partnering with food, pharma, and nutrition clients goes far beyond a transactional sale. It involves listening, adapting, and investing to keep product reliability high and problem-solving fast. We take personal pride in delivering each lot, knowing how much our output touches finished goods around the world. Every improvement, every challenge met, ultimately translates to safer and more effective nutrition for people and animals alike—a responsibility we take seriously, grounded in real factory and customer experience.
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