Products

DL-Panthenol

    • Product Name: DL-Panthenol
    • Chemical Name (IUPAC): rac-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide
    • CAS No.: 16485-10-2
    • Chemical Formula: C9H19NO4
    • Form/Physical State: White crystalline powder
    • Factroy Site: No. 1 Xuelin Street, Haining, Zhejiang, China
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Jiangxi Brother Pharmaceutical Co., Ltd.
    • CONTACT NOW
    Specifications

    HS Code

    626927

    Chemical Name DL-Panthenol
    Other Names Provitamin B5
    Appearance White crystalline powder
    Solubility Freely soluble in water and alcohol, insoluble in oils
    Molecular Formula C9H19NO4
    Molecular Weight 205.25 g/mol
    Odor Odorless
    Ph Range 5 Percent Solution 7.0 – 9.0
    Melting Point 64 – 69°C
    Cas Number 16485-10-2
    Stability Stable under recommended storage conditions
    用途 Commonly used in cosmetics and personal care products
    Storage Conditions Store in a cool, dry, well-ventilated area

    As an accredited DL-Panthenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing DL-Panthenol is packaged in a sealed, white plastic bottle containing 500 grams, featuring a secure screw cap and clear labeling.
    Container Loading (20′ FCL) For DL-Panthenol, a 20′ FCL typically holds 16–18 metric tons, packed in 25 kg fiber drums, ensuring safe bulk transport.
    Shipping DL-Panthenol is typically shipped in sealed, food-grade plastic or aluminum containers to protect it from moisture and contamination. It should be stored in a cool, dry, and well-ventilated area, away from strong oxidizing agents. Handle with care to avoid spillage. Transportation should comply with applicable regulations and safety guidelines.
    Storage DL-Panthenol should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from direct sunlight and incompatible substances. It is sensitive to moisture and heat, so keep it at temperatures below 40°C. Properly label the storage area and avoid exposure to strong oxidizing agents. Use protective equipment when handling and storing DL-Panthenol.
    Shelf Life DL-Panthenol typically has a shelf life of 24 months when stored in tightly closed containers, protected from light, moisture, and heat.
    Application of DL-Panthenol

    Applications of DL-Panthenol in Industrial Manufacturing

    As a dedicated producer of DL-Panthenol, we supply this material to several industrial sectors requiring strict quality control. Below, we highlight proven downstream manufacturing applications, each with specific compliance frameworks, dosage protocols, process roles, and end-product outputs based on actual global market sectors.

    1. Cosmetic and Personal Care Formulations

    Major personal care product formulators utilize DL-Panthenol within aqueous and emulsion systems for conditioning, moisturizing, and repairing benefits in finished goods like skin lotions, shampoos, hair conditioners, and facial creams. Production lines integrate our material during the water phase mixing step, optimizing for homogeneity in multi-phase systems. Batch records carefully document concentration, sourcing, and verification per regulatory filings and local market requirements. We maintain consistent purity, minimization of residual solvents, and validated microbiological profiles to meet frequent audits.

    Industry compliance standards

    • EU Cosmetic Regulation (EC) No. 1223/2009
    • China National Standards for Cosmetic Ingredients (GB/T 29665, 2013)
    • U.S. FDA 21 CFR 720 – Voluntary Cosmetic Registration Program (VCRP)
    • ISO 22716 GMP for Cosmetics Manufacturing

    Typical usage ratio

    • 0.2%–2.0% by weight, adjusted for desired conditioning effect, formulation type (rinse-off or leave-on), and sensory profile

    Downstream process integration

    • Added to deionized water phase under moderate agitation at 40–50°C prior to combination with oils or emulsifiers; pH adjustment required post-blending for stable finished product

    Final product types

    • Moisturizing shampoos and conditioners
    • Skin creams and lotions
    • Facial masks and serums
    • After-sun repair gels

    2. Pharmaceutical and Dermatological Preparations

    Pharmaceutical manufacturers in topical medication and medical skincare integrate our DL-Panthenol as a pro-vitamin additive for wound healing, anti-inflammatory, and skin recovery properties. Operations require full traceability in accordance with pharmacopeial monographs. Typical formulations include ointments, healing creams, and gels targeting minor skin injuries, burns, or irritations. Our PCI-inspected production lines support GMP documentation, stability protocols, and validated analytical methods for this sector.

    Industry compliance standards

    • European Pharmacopoeia (Ph. Eur.) Monograph 1095
    • United States Pharmacopeia (USP)
    • Good Manufacturing Practices (GMP) per ICH Q7/Q8
    • FDA Drug Master File (DMF) registration where applicable

    Typical usage ratio

    • 1.0%–5.0%, defined by the therapeutic claims, target population safety, and drug product classification

    Downstream process integration

    • Charged to aqueous vehicle post-solubilization steps; integrated at controlled temperatures to prevent hydrolysis; subjected to final in-process assay prior to release

    Final product types

    • Wound healing ointments
    • Burn and rash treatment creams
    • Medical skin repair gels
    • Anti-inflammatory topical solutions

    3. Veterinary Topical and Nutritional Products

    Veterinary product developers deploy DL-Panthenol for skin and coat conditioning in animals, as well as for the enhancement of oral supplements. In topical applications, manufacturers incorporate our material into sprays, creams, and gels intended for animal wound recovery and skin protection, while feed and oral care supplements use it for maintaining healthy skin and mucosa. Full compliance with animal health regulations and feed additive legislation is mandatory, and our production flow includes segregated lines and allergen management protocols for cross-contamination prevention.

    Industry compliance standards

    • European Union Regulation (EU) No 1831/2003 on additives for use in animal nutrition
    • FDA Center for Veterinary Medicine (CVM) feed ingredient listing
    • Ph. Eur. and USP Veterinary Monograph References when required
    • HACCP and ISO 9001:2015 for feed/animal-grade materials

    Typical usage ratio

    • Topical: 0.5%–3.0% depending on formulation and target species; Oral: 10–50 mg/kg feed based on nutritional supplementation plans

    Downstream process integration

    • For topical, dispersed in water or aqueous gel phase at 30–40°C; for feed, pre-blended with vitamins and minerals for homogenous distribution in final pelletizing or mixing stages

    Final product types

    • Veterinary skin creams and sprays
    • Animal wound care gels
    • Feed additives for livestock and pets
    • Pet oral health supplements

    4. Industrial Household and Institutional Cleaning Solutions

    Producers of high-quality household and institutional cleaners leverage DL-Panthenol for its skin-conditioning effect, particularly in formulations where consumer contact is frequent, such as hand dishwashing liquids, gentle surface cleaners, and institutional hand soaps. Our quality standards ensure minimal impurities that could trigger irritation or affect foaming and stability. Manufacturers introduce our ingredient during the surfactant blending process in controlled temperature vessels, securing batch reproducibility and long-term product transparency.

    Industry compliance standards

    • EU Detergents Regulation (EC) No 648/2004
    • U.S. EPA Safer Choice Standard for Formulators
    • ISO 9001:2015 Certified Quality Management
    • REACH Registration, Evaluation, Authorisation and Restriction of Chemicals

    Typical usage ratio

    • 0.1%–0.8% for regular cleaners; up to 1.5% for specialized skincare-focused products

    Downstream process integration

    • Loaded post-surfactant addition at 25–40°C; agitation continues until clear solution achieved; pH and viscosity tuned for target market specification

    Final product types

    • Moisturizing hand dishwash liquids
    • Liquid hand soaps for institutional use
    • Surface cleaners with skin contact claims
    • Sanitizing wipes and sprays

    5. Food Packaging and Food Contact Material Coatings

    Selected packaging manufacturers in the food industry apply DL-Panthenol within water-based coatings or edible films to enhance film flexibility and prevent brittleness, particularly in wrapping and edible strip markets. This application demands full traceability, strict migration testing, and compliance with food additive and food contact regulations applicable to different regions. Our lines for this sector ensure absence of contaminants that could leach or alter organoleptic properties of the food.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 on plastic and food contact materials
    • U.S. FDA CFR Title 21, Part 175.300 – Resinous and polymeric coatings
    • China GB 9685-2016 Standard for Food Contact Additives
    • Good Manufacturing Practice (GMP) for food packaging per EC 2023/2006

    Typical usage ratio

    • 0.1%–1.0% in film and coating blends, with precise adjustment based on tensile strength, flexibility requirements, and migration test results

    Downstream process integration

    • Premixed with polymer or starch dispersions before film casting or coating application on substrates; monitored for performance in accelerated aging and migration trials

    Final product types

    • Flexible edible films
    • Food wrapping materials
    • Coated paper packaging with food contact certification
    • Edible strips and wraps for confectionery

    Free Quote

    Competitive DL-Panthenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please contact us at +8615371019725 or mail to sales7@bouling-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@bouling-chem.com

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    Certification & Compliance
    More Introduction

    DL-Panthenol: Direct from Our Production Line

    Understanding DL-Panthenol

    Over the past two decades running our chemical plant, few ingredients have gained such a steady reputation among manufacturers as DL-Panthenol. Inside our reactors, each batch of this raw material goes through rigorous controls. What sets DL-Panthenol apart is its consistency and adaptability. It has become a backbone for personal care, cosmetics, and pharmaceutical preparations.

    For those looking for the chemistry: DL-Panthenol is the racemic mixture of D- and L- forms of panthenol. Unlike D-Panthenol, which acts as the biologically active form found in living organisms, DL-Panthenol supplies both forms equally, bringing about a broad-spectrum application. Our production lines turn out DL-Panthenol in its familiar white crystalline powder or clear, viscous liquid states. Purity checks regularly hit 99% or higher—these figures matter, especially for our customers using it in dermal formulations or hair conditioners.

    Why Manufacturers Value DL-Panthenol

    Through years of feedback, we have learned that formulators and processors rely on consistent quality and solubility above all else. DL-Panthenol blends easily with water and alcohol, making it a reliable choice for everything from shampoos to wound healing gels. In the cosmetics sector, formulators usually turn to DL-Panthenol for its trusted performance. It shows up in skin lotions, facial serums, hair conditioners, and even nail care solutions. Once applied, DL-Panthenol helps the skin attract and hold onto moisture, giving finished products a smoother, richer feel.

    Most buyers prefer the powder form for stability and ease of measurement during high-volume production. Handling liquid DL-Panthenol takes more care to avoid contamination, but it integrates quickly into water-based systems. Our standard specifications follow tight ranges for moisture content, heavy metal content, and residue on ignition. Technicians working on large scale dissolution lines will notice its almost immediate clarity on mixing, which saves time before batch filtration.

    Everyday Uses Backed by Experience

    Talking with customers from the personal care sector, DL-Panthenol often comes up as an ingredient you can trust. Its primary role revolves around skin and hair moisture. For example, shampoo factories integrate it for improved combability and to minimize split ends after frequent washes. Lotions benefit from its ability to support skin softness without leaving an unpleasant residue. We send out several tons each year to makers of hand creams, who value the long-lasting feel it provides even in harsh climates.

    Medicinal ointment producers have shared their positive feedback about using DL-Panthenol for wound care. In this space, each production lot undergoes purity testing more severe than any standard we hold for cosmetics. These producers have built reputations on rapid healing properties and customer comfort, and in these areas, DL-Panthenol delivers. Our own batch logs reflect this demand: medicinal and cosmetic DL-Panthenol grades rarely sit on our shelves for long.

    Comparing DL-Panthenol to Other Forms

    Within our facility, we manufacture both D-Panthenol and DL-Panthenol. D-Panthenol, the optically active form, is typically marked as pro-vitamin B5 and shows higher bioactivity in pharmaceutical and specialist skincare products. DL-Panthenol, while containing both isomers, offers cost advantages and the flexibility sought by many large-scale users. The L-isomer does not provide provitamin activity but serves as a functional humectant, which satisfies the needs of many industrial users.

    Clients often ask us about the difference between using pure D-Panthenol or the racemic mixed DL-Panthenol. We always encourage lab-scale pilot runs. For cost-sensitive applications and products where humectant function is more important than strict pharmacological action, DL-Panthenol answers the call. Makers of routine moisturizing creams or hair conditioners favor the racemic mix because it stretches the budget while maintaining performance. Pharmaceutical or cosmeceutical brands marketed as superior usually turn to pure D-Panthenol. Still, in most mainstream consumer products, the blend covers all bases.

    Formulation Realities from the Factory Floor

    From our experience, mixing DL-Panthenol with other ingredients rarely poses difficulties. Its compatibility remains high with anionic and non-ionic surfactants, which continue to dominate shampoo bases and bath gel formulations. Surfactant compatibility contributes to stable, finished products. If your batch process involves high temperatures or alkaline environments, you get reassurance from the thermal stability of our DL-Panthenol grade. As the operator overseeing production, I know shifts rarely see batches rejected due to precipitation or instability caused by panthenol.

    Engineers regularly consult with us about heating requirements, allowable pH, or reaction times during the mixing stage. DL-Panthenol holds up well in aqueous solutions across a moderate pH range. Our in-house testing aligns with field reports showing no discoloration or off-odors even during months of storage in warehouse conditions.

    Quality Stewardship—A Manufacturer’s Viewpoint

    Quality never takes a holiday in our plant. Each lot undergoes chemical titration, infrared spectrometry, and heavy metal analysis to root out any risk of contamination or off-grade stock. Customers often visit our production line, so transparency matters. Advanced filtration removes trace impurities, and water content checks take place at three different stages during production. Our lot tracking system prevents accidental mix-ups, so every drum of DL-Panthenol can be traced by day and technician.

    Sometimes rumors swirl about inconsistent foreign supply or adulterated product. Reliable partners want audit trails, so we maintain open records of batch testing and retain samples for up to three years. Since global price pressures lead to shifting sources of raw material, we secure our supply chain with qualified vendors for each key starting material, verified with trusted third-party labs. Each year, several customers share stories about switching to our product after facing issues elsewhere. Lost production time and customer complaints sting, so they value a consistent manufacturer relationship as much as the product itself.

    Meeting Industrial-Scale Demands

    On the industrial side, demand growth typically tracks with consumer awareness of healthy skin and hair. Top brands routinely scale up orders by season, and as a producer we watch order volumes spike around major promotional periods. Our plant can run around the clock to fill shipment backlogs. Large multinational brands depend on this reliability just as much as small, handcrafted goods operators. We deliver in drums or small containers according to customer preference.

    Logistics form the backbone of service to our bulk clients. Packaging engineers focus on drum liners and container seals that keep DL-Panthenol stable during long sea freight journeys. For customers in regions with turbulent climates, we offer guidance on safe storage and temperature controls based on first-hand experience in our own warehouses.

    Adapting to Regulatory Shifts

    Over the past five years, regulatory scrutiny on cosmetic raw materials has only increased. In response, we adjust testing and anti-contamination protocols so our DL-Panthenol grade meets the safety and purity standards set by authorities in North America, Europe, and Asia. Ingredient declarations, material safety data, and transport labeling all follow the latest regional requirements, streamlining approval for downstream manufacturers.

    Formulators must comply with updates to limits on impurities and allergens. By working closely with our compliance team, we stay ahead of these changes and help customers maintain certifications. If regulations swing toward tighter purity levels, we upgrade filtration or alter reaction protocols to ensure compliance. Many third-party agencies send regular inspection teams—our open plant policy means their audits rarely uncover surprises.

    Sustainability Through Experience

    In response to rising expectations around sustainability, we invested in closed-loop water systems and energy-efficient process heat recovery. Reducing waste chemicals ranks high on our list. DL-Panthenol generations have benefited from these advances in processing, which lower batch-to-batch variability and keep manufacturing costs predictable. Brands seeking to improve their environmental image look for reliable supply partners who actively reduce environmental impact, and our product fits that standard.

    Feedback from European brands this year asked for product origin transparency and “green” process certification. We track energy and water use on each batch and confirm the status of non-GMO sourcing for precursor materials. Without compromising on purity or test results, our team continues to pilot new processes using less energy and safer solvents. These are not just buzzwords; on the production floor, every percentage point trimmed from water waste or solvent inputs turns into a healthier balance sheet and a cleaner environment for our community.

    Support Beyond Delivery

    For every new collaboration, technical support plays a central role. We conduct blend trials with customers, monitor changes in output, and troubleshoot unforeseen compatibility issues. Some customers send their own scientists to shadow our staff during pilot runs, learning firsthand about solubility, dosing, and proper handling. On-site visits and video consultations mean that production scale-ups don’t hit unnecessary snags. Across industries, our team serves as a direct line to practical experience, not just a voice at the other end of an order form.

    Packaging and shipment depend on specific customer requirements. Climate, transit time, and storage conditions all get factored into our recommendations. Customers sometimes request pre-dissolved DL-Panthenol or special particle sizing to suit automated machinery. Over the years, we’ve built custom packaging solutions as needed. On hot days, we have staff overseeing cold storage containers, ensuring the product lands at your dock unchanged.

    Potential Challenges and How to Solve Them

    Customers sometimes report formulation haze, instability, or changes in final appearance when switching to a new DL-Panthenol supplier. Our technical team steps in, analyzing compatibility across surfactants, thickeners, and preservative systems to get to the root cause. Careful pH control and correct order of addition almost always resolve these issues.

    Another common question revolves around labeling and consumer claims. Since DL-Panthenol contains both D- and L- isomers, front panel claims about “pro-vitamin B5” may face regulatory questions in some markets. We encourage all customers to work closely with their legal departments and test formulations against local and export regulations to avoid future setbacks.

    Shelf life occasionally comes up, especially in products with long lead times or distribution in warm climates. Through our retention sample studies, DL-Panthenol remains stable for years when sealed and stored in a dry place away from direct sunlight. Proper warehouse rotation and container integrity form the backbone of long reliable shelf life.

    The Manufacturer’s Promise

    From batch logs to customer visits, our perspective as a long-time manufacturer ensures an unbroken chain of quality and direct accountability. DL-Panthenol’s place in modern formulations comes from hard-won experience—trials on the shop floor, feedback from formulators working long nights, and our own drive to innovate process and supply chains. Direct partnerships fueled by trust and grounded in shared goals drive every decision.

    Whether you build global brands or craft small-batch formulas, sourcing DL-Panthenol from a manufacturer means getting more than just a commodity—it’s an open line to expertise earned through decades of hands-on production. As standards change and consumer expectations climb, DL-Panthenol has proven time and time again to be the ingredient our customers rely on—delivered direct from our line to yours.