Products

1,2-Diethoxybenzene

    • Product Name: 1,2-Diethoxybenzene
    • Chemical Name (IUPAC): 1,2-Bis(ethoxy)benzene
    • CAS No.: 138-88-5
    • Chemical Formula: C10H14O2
    • Form/Physical State: Liquid
    • Factroy Site: No. 1 Xuelin Street, Haining, Zhejiang, China
    • Price Inquiry: sales7@bouling-chem.com
    • Manufacturer: Jiangxi Brother Pharmaceutical Co., Ltd.
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    Specifications

    HS Code

    834174

    Name 1,2-Diethoxybenzene
    Cas Number 2055-14-3
    Molecular Formula C10H14O2
    Molar Mass 166.22 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 246-248°C
    Melting Point -20°C
    Density 1.024 g/cm3 at 20°C
    Refractive Index 1.508-1.511
    Flash Point 104°C
    Solubility In Water Insoluble
    Smiles CCOC1=CC=CC=C1OCC
    Pubchem Cid 14665
    Synonyms Veratrole, diethyl ether; o-Diethoxybenzene
    Hazards Irritant

    As an accredited 1,2-Diethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 mL of 1,2-Diethoxybenzene; features a leak-proof screw cap and clear hazard labeling.
    Container Loading (20′ FCL) 1,2-Diethoxybenzene (20′ FCL): Typically loaded in 200 kg drums, 80 drums per container, totaling 16 metric tons net weight.
    Shipping **1,2-Diethoxybenzene** is typically shipped in tightly sealed containers made of compatible materials, such as amber glass bottles or HDPE containers, to prevent contamination and degradation. It should be labeled appropriately and transported in compliance with local, national, and international chemical safety regulations, ensuring protection from extreme temperatures and direct sunlight during shipping.
    Storage 1,2-Diethoxybenzene should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible substances such as strong oxidizing agents. Protect the chemical from moisture and direct sunlight. Ensure good ventilation in the storage area and clearly label the container to prevent accidental misuse or contamination.
    Shelf Life 1,2-Diethoxybenzene is stable under recommended storage conditions, with a typical shelf life of several years in tightly sealed containers.
    Application of 1,2-Diethoxybenzene

    Applications of 1,2-Diethoxybenzene in Industrial Manufacturing

    As a direct manufacturer, we supply 1,2-Diethoxybenzene for several specialized chemical industries with strict quality and compliance needs. The following real-world application sectors integrate this material as an advanced intermediate in established processing routes. Each segment outlines unique compliance frameworks, specific dosage norms, process intake points, and typical end products.

    1. Pharmaceutical Synthesis: Intermediate for API Production

    Manufacturers select 1,2-Diethoxybenzene as a critical intermediate during the multistep synthesis of various APIs, especially benzodioxole-containing molecules and specific antipsychotic drug precursors. The controlled ethoxylation pattern ensures high specificity during key condensation and cyclization reactions, minimizing side reactions that compromise yield and purity. Technicians typically feed the substance post-initial functionalization and before halogenation or ring closure steps. Careful adjustment of reaction conditions protects the integrity of the ethoxy groups, enabling formation of target ring systems with strict impurity controls.

    Industry compliance standards

    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 211: US FDA GMP for Finished Pharmaceuticals
    • European Pharmacopoeia 11.0 – Section on Intermediates
    • China Drug Administration: GMP for Chemical APIs

    Typical usage ratio

    • 20–35% of total intermediate batch mass, adjusted based on reaction pathway complexity and target molecule quantity

    Downstream process integration

    • Enters during mid-stage intermediate synthesis prior to core API assembly
    • Utilized in condensation or nucleophilic substitution stages
    • Handled in dedicated reactors with in-process purity monitoring

    Final product types

    • Antipsychotic drug intermediates
    • Benzodioxole-core APIs
    • Specialty antihistamines and adjunct actives

    2. Agrochemical Formulation: Synthesis of Selective Herbicide Intermediates

    The agrochemical sector relies on 1,2-Diethoxybenzene for its role in creating advanced intermediates used in the manufacture of selective phenoxy herbicides. Its reactivity profile allows for precise ether bridge formation, supporting the construction of herbicide molecules targeting broadleaf weeds without harming crops. Mixing engineers introduce the compound at a stage where controlled ethoxy cleavage is required, optimizing selectivity via regulated temperature and pH to minimize unwanted byproducts. Product stewardship teams monitor each batch for residual impurities specific to agricultural requirements.

    Industry compliance standards

    • FAO/WHO: Specifications and Codes of Practice for Pesticides
    • REACH Regulation (EC) No. 1907/2006
    • China GB 2763: Maximum residue limits for pesticides in food
    • EPA 40 CFR Part 180: Tolerances for pesticide chemicals in food

    Typical usage ratio

    • 10–28% relative to total batch mass, updated per target molecule pathway and desired crop selectivity

    Downstream process integration

    • Incorporated in early-stage phenol etherification steps
    • Feeds directly into subsequent halogenation and coupling with aliphatic acid derivatives
    • Blended in solvent-controlled reactors to prevent cross-contamination

    Final product types

    • Selective broadleaf herbicide concentrates
    • Intermediate stock for pre-plant soil treatment agents
    • Herbicide precursor blends for downstream formulating plants

    3. Industrial Dye Manufacturing: Precursor for Azo and Anthraquinone Dyes

    Technical teams in dye manufacturing facilities employ 1,2-Diethoxybenzene as an aromatic precursor that enhances chromophore stability for both azo and anthraquinone dye lines. Its electron-donating ethoxy groups facilitate C–C and N–N coupling reactions, which are essential for color intensity and chemical fastness. The compound is dosed after initial aromatic ring functionalization but before diazotization or anthraquinone assembly. Adjustments in temperature and pH are carefully managed to maximize yield and minimize side colors or reaction tars.

    Industry compliance standards

    • OEKO-TEX® Standard 100: Restrictions on harmful substances in textiles
    • ZDHC MRSL: Zero Discharge of Hazardous Chemicals Manufacturing Restricted Substances List
    • EN 71-3: Safety of Toys – migration of certain elements (applicable to textile dyes for toys)
    • REACH Annex XVII: Restrictions on polycyclic aromatic hydrocarbons in dyes

    Typical usage ratio

    • 8–17% of total dye batch mass, tuned by desired color depth and target substrate fiber

    Downstream process integration

    • Entered post-initial aromatic functional group introduction
    • Used in condensation stages for chromophore assembly
    • Feeds into continuous reactors linked to coloration control systems

    Final product types

    • Reactive azo textile dyes
    • Anthraquinone synthetic pigments for plastics
    • High-stability dispersion dyes for technical textiles

    4. Polymer Additive Manufacturing: Stabilizer Precursor for Specialty Resins

    Specialty polymer and resin producers incorporate 1,2-Diethoxybenzene as a building block for manufacturing phenolic-type stabilizers and antioxidant additives. Its ether substituents support tailored crosslinking reactions which enhance the thermal and oxidative stability of end-use plastic materials. Processing engineers introduce the ingredient during the pre-polymer modification step, ensuring uniform dispersion prior to final resin polymerization or compounding. Compliance experts maintain strict traceability for all additives to satisfy high-spec industry applications, including electrical insulation and consumer contact plastics.

    Industry compliance standards

    • UL 94: Flammability Standard for Plastic Materials
    • RoHS Directive 2011/65/EU: Restriction of hazardous substances in electronic equipment
    • FDA 21 CFR 177.2600: Elastomers for repeated use in food contact
    • ISO 9001:2015 for Quality Management in Polymer Processing

    Typical usage ratio

    • 3–9% of stabilizer additive mass, varies by polymer type and end-use performance requirements

    Downstream process integration

    • Injected at pre-polymer or pre-compounding stage
    • Combined in high-shear mixers before final resin extrusion
    • Feeds downstream to granulation or molding lines with traceability controls

    Final product types

    • Phenolic antioxidants for PP, PVC, ABS plastics
    • Heat-stabilized electrical insulation resins
    • Food-contact compliant elastomeric gaskets

    Free Quote

    Competitive 1,2-Diethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing 1,2-Diethoxybenzene: High-Purity Material for Sensitive Applications

    Trusted Quality from The Source

    For two decades in the manufacturing sector, we have refined our approach to meet the growing standards of both research and industry. The focus on 1,2-Diethoxybenzene, also known as ortho-diethoxybenzene, arose out of real conversations with chemical engineers and project leads who found standard grades didn’t always deliver the clarity or reproducibility necessary for high-precision applications. As direct manufacturers, we control each step of its journey, from reaction setup to filtration and final analysis.

    Product & Process Transparency

    Our 1,2-Diethoxybenzene comes from a tightly monitored synthesis, achieving purity levels that meet stringent needs defined during actual long-run pilot projects—not just on paper. We take pride in offering a crystalline liquid with a colorless to faintly pale appearance, free from foreign odor, with batch GC profiles consistently exceeding 99% main component area under curve (AUC). The melting and boiling range has been measured multiple times across production lots, and periodic re-testing during storage is standard practice at our site. Each shipment includes authentic, batch-specific data, straight from our internal quality team. You see the same numbers we use to qualify batches for further downstream synthesis or export.

    Applications Shaped by Collaboration

    We developed our purification protocol to meet requests from dye manufacturers who reported that standard technical grades left problematic by-products during sulfonation. That same feedback loop led to optimization for perfumery intermediates, particularly where fragrance profile depends on very specific substitution patterns. Academic teams working on phenolic resin development highlighted trace metal contamination as an obstacle, pushing us to install additional pre-cleaning steps on input solvents. These collaborations helped our team align 1,2-Diethoxybenzene production to requirements for functionalized material design, such as coupling reactions, advanced organometallic routes, and specialty aroma chemicals.

    From Reaction Kettle to Your Door: In-House Logistics

    Manufacturing on-site allows us to coordinate timing, packaging, and dispatch directly. The product never sits unsupervised in third-party warehouses, reducing risk of container mismatch, improper sealing, or cross-contamination. We use vessels and drums cleaned for aromatic ethers, and all packing is sealed in line with the requirements for aromatic chemicals transportation. Our in-house team handles any inquiries related to labeling requirements or specific packing formats, including glass bottles, PTFE-lined drums, or stainless steel canisters, depending on whether the application is analytical or for pre-polymer feedstock.

    Beyond the Lab: The Value of High-Purity Material in Industry Practice

    The impact of using pure 1,2-Diethoxybenzene reveals itself most clearly in downstream processing. In fine chemical manufacturing, the presence of residual aliphatic alcohols or unreacted starting material can trigger side reactions during catalytic transformations, leading to off-spec by-products and extra purification headaches. Electronic materials developers have found that trace by-products end up on product substrates, affecting electrical properties; feedback from this sector motivated us to install a secondary vacuum distillation step, further reducing impurities. This level of attention is only feasible for us because manufacturing and quality assurance are under one roof.

    What Sets 1,2-Diethoxybenzene Apart?

    In everyday work, similar materials like 1,4-Diethoxybenzene or monothio-substituted benzene ethers might appeal due to related chemical frameworks. Yet, substitution pattern matters—our clients in custom synthesis have pointed out how the ortho configuration of 1,2-Diethoxybenzene offers unique pathways during Friedel-Crafts acylation or alkylation, compared to the para isomer where steric hindrance and electronic effects diverge. Further, while some teams once relied on standard diethyl ether blends as a workaround, only the target compound provides the exact electron density required for modern-day cross-coupling strategies. Analytical chemists pursuing trace detection frequently encounter overlapping signals with less pure analogues, complicating identification or quantitation. With a consistent high-purity supply, such ambiguities disappear.

    Meeting Modern Environmental and Safety Demands

    A push for more sustainable workflows in the specialty chemicals field places new demands on every input. Over time, we’ve adopted waste minimization strategies at each step of our 1,2-Diethoxybenzene synthesis, adjusting reaction stoichiometry to reduce side streams and updating our solvent recovery systems. This attention pays off in cleaner overall product profiles and a lower environmental footprint. Handling aromatic ethers still calls for vigilance: safe delivery practices, secure labeling, compatible packaging, and prompt communication with receiving teams stand as non-negotiables. Strong cooperative work between manufacturing and outbound logistics teams delivers reliable shipments, backed by safety records that speak for themselves. Facility audits and documentation requests from partners are always welcome and promptly addressed.

    Specification Scrutiny: Beyond Standardized Testing

    Industry standards set minimum requirements, yet practical manufacturing always pushes for more. We know that some producers stop short at spot-testing a few parameters; our experience has shown the pitfalls when broader screening—the everyday practice in our plant—uncovers unseen quality issues. In-process controls check for not just residual reactants and moisture levels but also trace catalysts and extraneous aromatic species. Our long-term clients see these as more than data; they translate to fewer interruptions on production lines, shorter batch rework cycles, and smoother transitions to new synthetic protocols.

    Feedback and Continuous Improvement

    Direct conversations with formulators, analytics teams, and plant chemists keep our standards in motion. A recent project in the flavors industry led us to tighten the cut between acceptable and off-spec by-products, following a practical bottleneck where even faint background materials altered product aroma in tightly regulated profiles. Similar hands-on learning happens in plastics applications: we regularly review our anti-static packaging solutions to match requirements for sensitive polymerization processes. Customer feedback gathers in our internal database, directly shaping batch records and operational protocols, closing the loop between fieldwork and batch adjustments.

    Practical Differences from Other Suppliers: Internal Experience Matters

    Unlike vendors or brokers who operate at arm’s length, our team holds experience rooted in the manufacturing site. Daily challenges faced by our process operators—steering reaction conditions or managing inbound solvent purity—drive operational tweaks. Year-on-year, incremental improvements to reaction time or energy input bring visible gains, not just on efficiency, but in the clarity of final product lots. Our facilities audit every major raw material for possible cross-reactivity. While new customers sometimes expect only a transactional relationship, our approach is hands-on, focused, and responsive—traits that only direct production instills.

    Supporting Scale-Up and Custom Projects

    Clients working on scale-up benefit from insight into real-world variables: how the compound responds when heated for long periods, the exact point it enters decomposition, or how to clean vessels to prevent carry-over when switching between batches. Our staff regularly hosts short technical discussions with plant chemists or project engineers to review precise conditions—information we only feel confident sharing after years of running and tweaking these processes ourselves. For new uses in functional materials or advanced intermediates, we can adjust specifications and packaging protocols in a matter of days, not months, due to the proximity between our labs and production teams. This integrated model lets clients move from pilot trials to larger runs smoothly.

    Reducing Downstream Burdens for End-Users

    Chemists in specialty industries—including pharmaceuticals, fine fragrances, and performance polymers—invest significant energy managing supply chain reliability and unexpected quality shifts. 1,2-Diethoxybenzene produced in-house shows clear benefits on their end: reduced downtime, lower need for purification or blending, less labor in troubleshooting off-cycle outputs. The time saved from fewer false starts or batch recalls converts into more predictable output, helping teams focus attention on innovation, not firefighting old purity issues.

    Regulatory and Documentation Support Anchored in Practice

    Compliance holds weight for every batch. Years of experience have taught us not to cut corners—each product stage earns documentation confirming its status for international transit, and all labeling matches up with customs and regulatory checkpoints. Our compliance records tie directly to every production batch, organized for clarity, making it easy for partners to cross-check details as needed. We handle special requests for declaration or country-of-origin materials promptly, since our in-house regulatory advisors remain up to speed with the latest changes—not just relying on third-party summaries.

    Insights into Market Trends: Direct Dialogue Shapes Direction

    Chemical markets shift regularly as new synthetic strategies emerge. By participating in early pilot programs and following downstream results, we catch practical needs before they grow into industry-wide challenges. In the past year, surging interest in greener reactions prompted us to rethink some input materials, switching to more renewable sources where possible. Feedback from research labs and performance material developers provided the critical push for such upgrades, helping redirect procurement efforts well before new regulations set in. Our open-door policy for technical partnerships means we encourage regular dialogue and welcome unusual project requests.

    Beyond Commodity Thinking: Valuing Process Know-How

    Over-simplifying 1,2-Diethoxybenzene as a simple building block misses the expertise that shapes its quality. Making thousands of liters under strict conditions reveals the small but significant differences: the point where trace moisture creeps in during warm months, the need to stagger distillation schedules to avoid carry-over, and the decision to skip a promising shortcut that adds risk of unwanted oligomerization. Lessons learned after dealing with stuck reactions or off-color lots inform every new batch. The hands-on perspective fixes minor issues before they become major problems, protecting consistency from batch to batch.

    Adaptable Batch Sizes and Flexible Lead Times

    Markets don’t stand still, and lab schedules rarely fit into predictable timelines. We’ve structured our plant and supply chain management to ship anywhere from small R&D ampoule lots up through ton-scale shipments. Decision makers appreciate not waiting weeks for a change in pack size, or dealing with sudden out-of-stock notices. Our direct control means buffer stocks are built up for core users, with notification systems for spike demands. Clients running new projects benefit from this flexibility, rolling out prototypes without lengthy supply chain negotiations.

    Delivering Consistency: Not Just a Buzzword

    Customers monitoring batch-to-batch reproducibility in their synthesis value more than simple purity figures. The consistency in odor, refractive index, and trace impurity profile matters in high-precision applications, such as the synthesis of sensitive boronic acids or downstream pharmaceutical intermediates. Our routine quality control team checks against historical records and flags outliers, reviewing causes whether from raw material shifts, temperature swings, or equipment upgrades. This focus reduces risk for our clients downstream, reinforcing trust built over long collaborations.

    The Long-Term Manufacturer Perspective

    Sustained manufacturing brings perspective unavailable to transient traders: knowing which solvent switches lead to faster reaction rates, which delivery routes minimize transit residuals, which documentation shortcuts never pan out. Facility visits teach us that practical reliability sometimes means prepping for surprise variances—weather conditions affecting inbound material storage, or equipment fouling changing subtle aspects of the product profile. Our site teams develop workarounds rooted in field experience, not theoretical planning, because long-term output depends on translating hands-on learning into practice.

    Facing Tomorrow: Upgrades and Opportunities

    As new frontiers open in high-performance materials, teams evaluating 1,2-Diethoxybenzene as a starting point for extended frameworks, energetic materials, or tailored ligands count on fast feedback loops. Our lab collaborates with project leads to tweak process conditions or investigate alternative purification pathways—another advantage of manufacturing and R&D working side-by-side. We stay open to experimental feedback and push for improvements, investing time and resources because direct experience with production often points to profitable innovations soon after a change in end-market demand.

    Why Direct Partnership Makes a Real Difference

    The future of specialty chemicals rests not just on the availability of building blocks, but in the working relationships that shape product and supply. Customers who come straight to manufacturers access more than the material; they benefit from candid answers, historical data sets, and shared learning from every batch that came before. Open communication ensures that one-off project requests do not take weeks to process or get derailed by chain-of-command confusion. This direct approach, cultivated over years of hands-on production, fits not just the needs of today but the demands of a fast-shifting market, adding security and value that chain brokers can’t provide.

    Ultimate Value: Trust Built Through Experience

    Direct manufacturing experience composes the backbone of confidence in materials like 1,2-Diethoxybenzene. Built on years of cumulative knowledge, field feedback, and steadily upgraded procedures, our approach anchors reliability in real practice—not just quarterly statistics. This perspective gives customers a clearer pathway to streamlined production, successful scale-ups, and more ambitious designs, grounded in material you can trust each time you receive it.